PrEP

PrEP1 – Pilot study

Attention: PrEP1 study has ended. Interested person may contact ceidstudy@cuhk.edu.hk for updates on new projects.

Aim and objectives

The project aims to serve as a feasibility study in making PrEP available to MSM at high risk of infection on a trial basis.

The objectives are, to:

1. test the acceptability of partially self-financed daily PrEP
2. examine the pattern of adherence to daily PrEP
3. evaluate the practicability of an incentivized model for PrEP
4. trial-run the system for monitoring the use of PrEP.

The Joint Chinese University of Hong Kong – New Territories East Cluster Clinical Research Ethics Committee has approved this study (Ref. No.: 2016.470) and is authorised to access the participants’ records related to the study for ethics review purpose. For enquiry regarding clinical research ethics, please contact the Committee at crec@cuhk.edu.hk and phone at 2632 3935.

Study design

Participants will be followed up for 48 weeks. PrEP will be prescribed to participants in the first 30 weeks on a partial payment basis. During this prescription period, participants will have to take medicine daily; visit the clinic regularly for body check-up, HIV and STI tests, complete questionnaire, make payment and collect prescription. At week 48, participants will be contacted for follow-up questionnaire.

Eligibility criteria

To join the study, you must:

1. be male, aged 18 or above, and had anal sex with another man; and
2. normally reside in Hong Kong; and
3. have never used PrEP; and
4. be inclined to have unprotected anal sex in the coming months; and
5. be willing to partly pay for PrEP; and
6. be HIV negative; and
7. be HBsAg negative; and
8. have normal renal function

Flow chart of the study

Body check-up & tests:

• Renal function
• HBsAg
• HIV
• Syphilis, NG/CT

Urine samples will be collected.
Fingerprick rapid tests will be performed.